Jean-François Toussaint, shugaban bincike da ci gaban duniya na Sanofi Pasteur, ya yi gargadin cewa nasarar rigakafin mRNA a kan Covid ba ta ba da tabbacin sakamako irin wannan na mura ba.
"Muna bukatar mu kasance masu tawali'u," in ji shi."Bayanan za su gaya mana idan yana aiki."
Amma wasu nazarin sun ba da shawarar cewa rigakafin mRNA na iya tabbatar da ƙarfi fiye da na gargajiya.A cikin nazarin dabbobi, allurar mRNA da alama suna ba da babban kariya daga ƙwayoyin cuta na mura.Suna sa tsarin garkuwar jikin dabbobi su kera ƙwayoyin rigakafin ƙwayoyin cuta, da kuma horar da ƙwayoyin rigakafi don kai hari ga ƙwayoyin cuta.
Amma watakila mafi mahimmanci ga mura, ana iya yin rigakafin mRNA cikin sauri.Gudun masana'antar mRNA na iya ƙyale masu yin rigakafin su jira wasu ƙarin watanni kafin su ɗauki irin nau'in mura don amfani, mai yuwuwar haifar da ingantacciyar wasa.
"Idan za ku iya ba da garantin kashi 80 a kowace shekara, ina tsammanin hakan zai zama babbar fa'ida ga lafiyar jama'a," in ji Dr. Philip Dormitzer, babban jami'in kimiyya na Pfizer.
Har ila yau, fasahar ta sauƙaƙe wa masu yin rigakafin mRNA don ƙirƙirar haɗin gwiwa.Tare da kwayoyin mRNA don nau'ikan mura daban-daban, kuma suna iya ƙara ƙwayoyin mRNA don cututtukan numfashi daban-daban.
A wani gabatarwa na Satumba 9 ga masu zuba jari, Moderna ya raba sakamako daga wani sabon gwaji wanda masu bincike suka ba da allurar rigakafin berayen da suka hada mRNAs don ƙwayoyin cuta na numfashi guda uku: mura na yanayi, Covid-19 da ƙwayar cuta ta gama gari da ake kira ƙwayar cuta ta syncytial, ko RSV.Berayen sun samar da manyan matakan kariya daga ƙwayoyin cuta guda uku.
Wasu masu bincike sun kasance suna neman maganin mura na duniya wanda zai iya kare mutane shekaru da yawa ta hanyar karewa nau'ikan mura.Maimakon harbin shekara-shekara, mutane na iya buƙatar ƙarfafawa kawai a cikin ƴan shekaru.A cikin mafi kyawun yanayi, allurar rigakafi ɗaya na iya yin aiki har tsawon rayuwa.
A Jami'ar Pennsylvania, ƙungiyar masu bincike karkashin jagorancin Norbert Pardi suna haɓaka rigakafin mRNA waɗanda ke ɓoye sunadaran ƙwayoyin cuta na mura waɗanda ke canzawa ba da daɗewa ba.Gwaje-gwajen dabbobi sun nuna cewa waɗannan alluran rigakafin za su iya yin tasiri daga shekara zuwa shekara.
Ko da yake Moderna ba ya aiki a kan allurar rigakafin mura ta duniya a halin yanzu, "hakika abu ne da za mu yi sha'awar nan gaba," in ji Dokta Jacqueline Miller, shugaban kamfanin bincike kan cututtuka.
Ko da allurar rigakafin mura na mRNA sun yi daidai da tsammanin, tabbas za su buƙaci ƴan shekaru don samun amincewa.Gwaji don rigakafin mura na mRNA ba za su sami babban tallafin gwamnati da allurar Covid-19 suka yi ba.Haka kuma masu gudanarwa ba za su ƙyale su su sami izinin gaggawa ba.Cutar mura ta zamani ba ta zama sabon barazana ba, kuma ana iya tunkarar ta da alluran rigakafi masu lasisi.
Don haka masana'antun za su ɗauki dogon hanya zuwa cikakkiyar yarda.Idan gwajin asibiti na farko ya yi kyau, masu yin alluran rigakafin za su ci gaba zuwa manyan gwaje-gwajen da ka iya buƙatar yaduwa ta cikin lokutan mura da yawa.
"Ya kamata ya yi aiki," in ji Dokta Bartley na Jami'ar Connecticut."Amma a fili shi ya sa muke yin bincike - don tabbatar da 'ya kamata' da 'yi' abu ɗaya ne."
Lokacin aikawa: Afrilu-21-2022